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Manufacturer(s) of Artemisinin in Pakistan.

AmsonHighnoon

Artemisinin

Overview

Artemisinin is an antimalarial, belongs to sesquiterpene lactone endoperoxide group. Artemisinin is derived from the weed qing hao (Artemisia annua), also called as wormwood or annual wormwood. The medicinal value has been known for more than 2000 years. It and related drugs are the most rapidly acting, effective and safe drugs for the treatment of severe malaria, including infection due to chloroquine and mutidrug-resistant strains of Plasmodium falciparum. It should not be used for prophylaxis of malaria or treatment of mild attacks.

Category:

Primary Characterstics

Molecular Structure of Artemisinin
. It is of Natural origin and belongs to Sesquiterpene lactone. . The Molecular Weight of Artemisinin is 282.30.

Pharmacokinetics

Volume of distribution is found to be 20 liter . Plasma half life is 2-3.2 hr.

Indications

Artemisinin is primarily indicated in conditions like Chloroquine resistant malaria, Complicated and severe malaria, Uncomplicated malaria.

Contraindications

Artemisinin is contraindicated in conditions like Malaria prophylaxis.

Drug Interactions

No data regarding the interactions of Artemisinin was found.

Interference in Pathology

No data regarding the pathological interferences produced by Artemisinin is available.

Side Effects

The severe or irreversible adverse effects of Artemisinin, which give rise to further complications include Jaundice, Neurotoxicity, Cardiovascular toxicity.

The signs and symptoms that are produced after the acute overdosage of Artemisinin include Cardiovascular disturbances.

The symptomatic adverse reactions produced by Artemisinin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Nausea, Vomiting, Fever, Abdominal cramps, Tinnitus, Abdominal pain, Skin rashes, Sweating, Pruritus, Hypotension, Somnolence, Darkening of urine, Decreased reticulocytes, Transient low fever.

Available Brands

Click on the appropriate strength of the dosage form to view its available brands.

Single Ingredient

Susp: 80 ml,
Tabs: 60 mg,

Dosage

Artemisinin's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

100 to 200 mg/day150 (150)As recommended.oral

Paedriatic Dosage ( 20 Kg. )

No data regarding the Paedriatic dosage details of Artemisinin is available.

Neonatal Dosage ( 3 Kg. )

No data regarding the neonatal dosage details of Artemisinin is available.

High Risk Groups

Drug should not be given to Pregnant Mothers, and Cardiac / Hypertensive Patients.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Warning / Precautions

Care should be taken when using to treat the women being pregnant with in three months or patients with vomiting severely.

Storage Conditions

Tab, Caps

Store . Protect from Sunlight, Moisture and Heat.

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