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Manufacturer(s) of Terlipressin in Pakistan.

FerozsonRotexWilsons

Terlipressin

Overview

A vasopressin analogue, which is used to control bleeding from esophageal varices . It is administered intravenously.

Category:

Primary Characterstics

. It is of Synthetic origin and belongs to Peptide. . The Molecular Weight of Terlipressin is 1227.40.

Pharmacokinetics

Volume of distribution is found to be 0.7 l/kg . Renal Excretion accounts for < 0.1 % unchanged and plasma half life is 24 min.

Indications

Terlipressin is primarily indicated in conditions like Bleeding from oesophageal varices, Bleeding oesophageal varices.

Contraindications

Terlipressin is contraindicated in conditions like Vascular disease.

Drug Interactions

No data regarding the interactions of Terlipressin was found.

Interference in Pathology

No data regarding the pathological interferences produced by Terlipressin is available.

Side Effects

The severe or irreversible adverse effects of Terlipressin, which give rise to further complications include Cardiac arrhythmias, Angina, Abdominal cramps.

Terlipressin produces potentially life-threatening effects which include Bradycardia, Myocardial infarction, Cardiac failure. which are responsible for the discontinuation of Terlipressin therapy.

The signs and symptoms that are produced after the acute overdosage of Terlipressin include Hypertension, Increase in BP, Water retention.

The symptomatic adverse reactions produced by Terlipressin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Abdominal cramps, Weakness of the leg, Skin pallor.

Available Brands

Click on the appropriate strength of the dosage form to view its available brands.

Single Ingredient

Inj: 1 mg,

Dosage

Terlipressin's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

No data regarding the Adult dosage details of Terlipressin is available.

Paedriatic Dosage ( 20 Kg. )

No data regarding the Paedriatic dosage details of Terlipressin is available.

Neonatal Dosage ( 3 Kg. )

No data regarding the neonatal dosage details of Terlipressin is available.

High Risk Groups

Drug should not be given to Pregnant Mothers, patients suffering from Liver Malfunction, and Geriatrics.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Warning / Precautions

Avoid use in patients with chronic nephritis with nitrogen retension. Use with caution and in small doses in patients with vascular disease, especially of coronary arteries. It should be given with care to patients with asthma, migrane, epilepsy, heart failure or hypertension. Fluid retension should be adjusted to avoid hyponatraemia.

Storage Conditions

Ampuls, Vial

Store at room temperature. Protect from Sunlight.

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