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Itopride (HCl)


Itopride (HCl) is a substituted benzamide, which is used for its prokinetic and antiemetic properties. The actions, uses and adverse effects similar to that of metaclopramide.


Primary Characterstics

belongs to Benzamide. . The Molecular Weight of Itopride (HCl) is 394.90.


Oral absorption of Itopride (HCl) is found to be 30% ±30. Plasma protien binding is 96%. and metabolism is reported Hepatic. Renal Excretion accounts for Urine .


Itopride (HCl) is primarily indicated in conditions like Dyspepsia, Gastro-esophageal reflux disease, Nausea and vomiting, and can also be given in adjunctive therapy as an alternative drug of choice in Anorexia, Heart burn.


Drug Interactions

No data regarding the interactions of Itopride (HCl) was found.

Interference in Pathology

  • Elevations of SGPT and SGOT
  • Increased Alkaline Phosphatase Levels
  • Elevation in ALT or AST

Side Effects

The symptomatic adverse reactions produced by Itopride (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Diarrhea, Constipation, Redness, Tremor, Thrombocytopenia, Leucopenia.

Available Brands

Click on the appropriate strength of the dosage form to view its available brands.

Single Ingredient

Tabs: 50 mg, 150 mg,
Tabs SR: 50 mg,
Caps: 150 mg,

Multi ingredient

Tabs: 50 mg,


Itopride (HCl)'s dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

50 mg50 (50)8 hourlyPOShould be taken before meal.
150 mg150 (150)24 hourlyPO

Paedriatic Dosage ( 20 Kg. )

No data regarding the Paedriatic dosage details of Itopride (HCl) is available.

Neonatal Dosage ( 3 Kg. )

No data regarding the neonatal dosage details of Itopride (HCl) is available.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Warning / Precautions

Itopride should be used with special caution in the young and the elderly. Little information is available at this time regarding the safe use of itopride during pregnancy.

Storage Conditions

Store Between 15°C-30°C.

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