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Manufacturer(s) of Flupenthixol (HCl and Decanoate) in Pakistan.


Flupenthixol (HCl and Decanoate)


Flupenthixol (HCl and Decanoate) is a tranquillizer. Flupenthixol (HCl and Decanoate) is used in depressive and anxiety states associated with inertia and apathy.


Primary Characterstics

Molecular Structure of Flupenthixol (HCl and Decanoate)
belongs to Thioxanthene. It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Antidepressant Tricyclic pharmacological group.The Molecular Weight of Flupenthixol (HCl and Decanoate) is 507.40.
Its pKa is 3.4.


Oral absorption of Flupenthixol (HCl and Decanoate) is found to be 82.5% ±2.5. Volume of distribution is found to be 14 l/kg and plasma protien binding is >95%. Presystemic metabolism is noted to be 40% and metabolism is reported extensive by liver. Renal Excretion accounts for minor and plasma half life is 35 hr.



Flupenthixol (HCl and Decanoate) is contraindicated in conditions like Parkinsonism,Coma.

Drug Interactions

Flupenthixol (HCl and Decanoate) is known to interact with other drugs, the details of drug interactions is as follows:

Metoclopramide (HCl)
VORICONAZOLEAdditive QTc prolongation may occur. Consider alternate therapy or monitor for QTc prolongation

These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Interference in Pathology

No data regarding the pathological interferences produced by Flupenthixol (HCl and Decanoate) is available.

Side Effects

Flupenthixol (HCl and Decanoate) produces potentially life-threatening effects which include Tachycardia, Cardiac arrhythmias, Neuroleptic Malignant Syndrome, B.P instability. which are responsible for the discontinuation of Flupenthixol (HCl and Decanoate) therapy.

The signs and symptoms that are produced after the acute overdosage of Flupenthixol (HCl and Decanoate) include Convulsions, Coma, Hyperthermia, Shock, Somnolence.

The symptomatic adverse reactions produced by Flupenthixol (HCl and Decanoate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dry mouth, Weight gain, Loss of libido, Tremor, Menstrual irregularity, Muscle rigidity, Transient insomnia, Erectile disturbance, Breast engorgement.

Available Brands

Click on the appropriate strength of the dosage form to view its available brands.

Single Ingredient

Inj: 20 mg, 40 mg, 100 mg,
Inj SR: 20 mg/ml, 40 mg/ml, 100 mg/ml,
Tabs: 1 mg, 3 mg, 0.5 mg, 0.25 mg,

Multi ingredient

Tabs: 0.5 mg,


Flupenthixol (HCl and Decanoate)'s dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

1 to 2 mg1.5 (1.5)24 hourlyPOFor depression Max dose 3 mg.
20 to 40 mg30 (30)As recommended.POFor psychosis. Initialy 20 mg.

Paedriatic Dosage ( 20 Kg. )

Not Recommended in this Age Group

Neonatal Dosage ( 3 Kg. )

No data regarding the neonatal dosage details of Flupenthixol (HCl and Decanoate) is available.

High Risk Groups

Drug should not be given to Pregnant Mothers, and Neonates.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Warning / Precautions

Flupenthixol is not recommended in state of excitement or overactivity,including mania.

Storage Conditions


Store Below 25°C. Protect from Sunlight.


Store Below 40°C. Protect from Sunlight and Moisture.

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