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Citicoline

Overview

Citicoline (Na) increases the blood flow in brain and used in the treatment of cerbro-vascular disorders such as ischaemic stroke and head injury.

Category:

Primary Characterstics

Molecular Structure of Citicoline
Citicoline also known as CDP-Choline, CDP-Choline, CDP-Choline. Citicoline (Na) is the derivative of Citicoline. It is of Synthetic origin and belongs to Choline Cytidine. It belongs to Psychotherapeutic Drugs pharmacological group.The Molecular Weight of Citicoline is 488.30.

Pharmacokinetics

Metabolism is reported Hepatic. Plasma half life is 24 hr.

Indications

Citicoline is primarily indicated in conditions like Cardiac stroke, Head trauma, Ischaemic heart disease, Paralysis of lower extremities, and can also be given in adjunctive therapy as an alternative drug of choice in Parkinson's disease.

Contraindications

Citicoline is contraindicated in conditions like Unconciousness,Pregnancy,Brain surgery,Breast feeding.

Drug Interactions

No data regarding the interactions of Citicoline was found.

Interference in Pathology

No data regarding the pathological interferences produced by Citicoline is available.

Side Effects

The severe or irreversible adverse effects of Citicoline, which give rise to further complications include Hypotension.

The symptomatic adverse reactions produced by Citicoline are more or less tolerable and if they become severe, they can be treated symptomatically, these include Excitement, Insomnia.

Available Brands

Click on the appropriate strength of the dosage form to view its available brands.

Single Ingredient

Inj: 1 g/ml, 100 mg/ml, 125 mg/ml, 250 mg/ml,
Drops: 0.01 %w/v,
Syrup: 500 mg/5ml,

Dosage

Citicoline's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

1 g1 (1)24 hourlyIVFor 4 weeks.
200 to 600 mg400 (400)As recommended.POTotal dose can be given as 2 divided doses. For 6 weeks.

Paedriatic Dosage ( 20 Kg. )

Not Recommended in this Age Group

Neonatal Dosage ( 3 Kg. )

Not recommended in this age group

High Risk Groups

Drug should not be given to Pregnant Mothers.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Warning / Precautions

For patients with acute, severe and progressive disturbances of consciousness due to head injury and brain surgery, Citicoline injection should be administered in conjunction with hemostatics and intracranial pressure relieving drugs, or treatment such as hypothermy.

Storage Conditions

Inj, syrups

Store in a well closed container, . Protect from Sunlight, Moisture and Heat.

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