Sign in or Sign up

User ID


Remember me - forgot password


Sign up or Sign in

Name (in full)

Email address


Confirm Password


Betahistine (HCl)


Betahistine (HCl) is a histamine analogue used as a vasodialtor to reduce the frequency of attacks of dizziness in Menier'e disease, administered orally.


Primary Characterstics

. It is of Synthetic origin and belongs to Amino Pyridine. It belongs to Histamine agonist pharmacological group on the basis of mechanism of action and also classified in H3 Antagonist pharmacological group.The Molecular Weight of Betahistine (HCl) is 209.10.
Its pKa is 3.5.


Oral absorption of Betahistine (HCl) is found to be 100% . Plasma protien binding is 0-5%. and metabolism is reported via Liver. Renal Excretion accounts for 85-90% and plasma half life is 3.5 hr.


Betahistine (HCl) is primarily indicated in conditions like Hearing loss, Menieres disease, Tinnitus, Vertigo.


Betahistine (HCl) is contraindicated in conditions like Asthma,Peptic ulcer,Phaeochromocytoma,Rhinitis,Urticaria.

Drug Interactions

Betahistine (HCl) is known to interact with other drugs, the details of drug interactions is as follows:

Diphenyl Pyraline

These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Interference in Pathology

No data regarding the pathological interferences produced by Betahistine (HCl) is available.

Side Effects

The signs and symptoms that are produced after the acute overdosage of Betahistine (HCl) include Nausea, Vomiting, Seizures, Dyspepsia, Ataxia.

The symptomatic adverse reactions produced by Betahistine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Nausea, Dyspepsia.

Available Brands

Click on the appropriate strength of the dosage form to view its available brands.

Single Ingredient

Tabs: 8 mg, 16 mg, 24 mg,


Betahistine (HCl)'s dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

16 mg16 (16)8 hourlyPOInitial, increase dose as per response
24 to 48 mg36 (36)24 hourlyPOMaintenance.

Paedriatic Dosage ( 20 Kg. )

Not Recommended in this Age Group

Neonatal Dosage ( 3 Kg. )

Not recommended in this age group

High Risk Groups

Drug should not be given to Pregnant Mothers, and Neonates.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Warning / Precautions

Betahistine should not be given to neonates, childrens, during pregnancy and lactation and in patients with pheochromocytoma. It should be used with caution in patients with asthma or peptic ulcer.

Storage Conditions


Store in a well closed container, at room temperature, Below 30°C.

comments powered by Disqus