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Manufacturer(s) of Zolpidem (Tartrate) in Pakistan.


Zolpidem (Tartrate)


Zolpidem (Tartrate) is a non-benzodiazepine sedative-hypnotic for the short-term treatment of insomnia. Although chemically unrelated to other hypnotics such as the benzodiazepines or barbiturates, zolpidem does share some pharmacological actions with these drugs. Unlike the benzodiazepines, zolpidem produces muscle relaxation and anticonvulsant effects only at doses much higher than the hypnotic dose. Zolpidem has a short half-life and no active metabolites. Therefore, a next-day "hangover" effect and CNS depression are less for zolpidem than the barbiturates. Treatment of insomnia with zolpidem should be restricted to a period of 7-10 days. Zolpidem received FDA approval in 1993.


Primary Characterstics

Molecular Structure of Zolpidem (Tartrate)
belongs to Imidazopyridine. It belongs to Chloride Channel opener (Gaba operated) pharmacological group on the basis of mechanism of action and also classified in Sedatives and Hypnotics pharmacological group.The Molecular Weight of Zolpidem (Tartrate) is 764.90.


Plasma protien binding is 92 %.


Zolpidem (Tartrate) is primarily indicated in conditions like Insomnia, Nausea, vertigo, labyrinthine disorders.


Zolpidem (Tartrate) is contraindicated in conditions like Myasthenia gravis,Psychosis,Pulmonary insufficiency,Respiratory depression,Sleep apnea syndrome.

Drug Interactions

Zolpidem (Tartrate) is known to interact with other drugs, the details of drug interactions is as follows:

Phenytoin (Na)
VORICONAZOLEVoriconazole may increase the serum concentration of zolpidem by decreasing its metabolism. Consider alternate therapy or monitor for changes in the therapeutic and adverse effects

These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Interference in Pathology

No data regarding the pathological interferences produced by Zolpidem (Tartrate) is available.

Side Effects

The severe or irreversible adverse effects of Zolpidem (Tartrate), which give rise to further complications include Dementia.

The symptomatic adverse reactions produced by Zolpidem (Tartrate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Confusion, GI upset, Depression, Tremor.

Available Brands

Click on the appropriate strength of the dosage form to view its available brands.

Single Ingredient

Tabs: 10 mg, 12.5 mg, 6.25 mg,


Zolpidem (Tartrate)'s dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

10 mg10 (10)24 hourlyPO

Paedriatic Dosage ( 20 Kg. )

Not recommended in this age group

Neonatal Dosage ( 3 Kg. )

Not recommended in this age group

High Risk Groups

Drug should not be given to patients suffering from Liver Malfunction.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Warning / Precautions

Zolpidem hemitartrate should be used during pregnancy or lactation only if clearly needed. It should be used with caution in patients with any pre-existing kidney disease, liver disease, lungs disease, history of drug dependence or depression, breathing problems or if have any allergy.

Storage Conditions


Store Below 40°C. Protect from Sunlight and Heat.

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