Cabergoline
Overview
Cabergotune is ergot derivatives is a dopamine D2-agonist with action and uses similar to bromocriptine. Cabergoline is used after pregnancy to suppress unwanted breast milk secretion and to facilitate conception when infertility is associated with high prolactin level. It may also be used in parkinson's disease, prolactin-producing tumors and to adjust various hormone levels in certain diseases (ovarian diseases).
Categories
- 18 Hormones and other endocrine drugs and contraceptives
Primary Characterstics
Indications
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Pharmacokinetics
Plasma protien binding is 41-42%. Renal Excretion accounts for 1.92% and plasma half life is 62-91 hr.
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Contraindications
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Side Effects
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Dosage
Cabergoline's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| | | PO | prevention of lactation 1mg as single dose: suppression of established lactation 250 mcg every 12 hrs for 2 days |
| | | PO | Hyperprolacdinaemic disorders: (0.25-2 mg weekly) |
| 1 to 1 mg/day | 1 (1) | As recommended. | PO | For parkinson''s disease: Increase by increments of 0.5-1 mg at 7-14 day interval. Man 3 mg/day. |
Paedriatic Dosage (20kg)
|
| | | | Not Recommended in this Age Group |
Neonatal Dosage (3kg)
|
| | | | Not recommended in this age group |
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Cabergoline
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