Irinotecan (HCl Trihydrate)
Overview
Irinotecan (HCl Trihydrate) is an antineoplastic agent, also known as anticancer drugs. Irinotecan (HCl Trihydrate) is a semisynthetic derivative of alkaloid camptothecin. Irinotecan (HCl Trihydrate) is a pro-drug and is effective in the treatment of different cancers to slow or stop the growth of cancererous or abnormal cells. Irinotecan (HCl Trihydrate) is used in combination of different anticancer drugs to achieve best results and to reduce toxicity or side effects. It has been recently approved for clinical use.
Categories
- 8 Antineoplastics, immunomodulators and drugs used in palliative care
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Irinotecan (HCl Trihydrate)'s dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 125 to 350 mg/sq.meter | 240 (237.5) | As recommended. | IV Inf | As recomemnted,Over30-90 min., every 3-4 week |
Paedriatic Dosage (20kg)
|
| | | | Not recommended in this age group |
Neonatal Dosage (3kg)
|
| | | | Not recommended in this age group |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Irinotecan (HCl Trihydrate)
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Manufacturers of
Irinotecan (HCl Trihydrate)
in Pakistan
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