Cilastatin (Na)

Overview

Cilastatin (Na) is an aihibitor of enzyme dehydropeptidase I, found in the brush border of the renal tubules. Cilastatin (Na) is administered concomitantly with the antibiotic Imipenem to prevent its renal metabolism to microbiologically inactive and potentially nephrotoxic products. Cilastatin has no bacterial activity itself, and does not affect the antibacterial activity of imipenem.

Categories

• 6 Anti-infective drugs
  • 6.2 Antibiotics, systemic
    • 6.2.1 Beta-lactam drugs
      • 6.2.1.4 Other inhibitors of cell wall synthesis

Page headings

Primary Characterstics

Indications

Pharmacokinetics

Contraindications

Cilastatin (Na) is contraindicated in conditions like Hypersensitivity to any component of product.

Drug Interactions

Side Effects

Dosage

Cilastatin (Na)'s dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
No data regarding the Adult dosage details of Cilastatin (Na) is available.
Paedriatic Dosage (20kg)
No data regarding the Paedriatic dosage details of Cilastatin (Na) is available.
Neonatal Dosage (3kg)
No data regarding the neonatal dosage details of Cilastatin (Na) is available.

High Risk Groups

Warning / Precautions

Storage Conditions

Interference in Pathology

Brands / Trade Names of Cilastatin (Na)

Manufacturers of Cilastatin (Na) in Pakistan

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