Quinupristin
Overview
Quinupristin is semisynthetic derivative of naturally occuring pristinamycins, produced by Streptomyces pristinaespiralis.It is a protein synthesis inhibitor that binds the 50 S ribosomal subunit with inhibition of polypeptide elongation and early termination of protein synthesis.Quinupristin is approved for treatment of infections caused by Vancomycin-resistant strains of E. faecium and complicated skin and skin structure infections caused by Methicillin resistant strains of S. aureuses or S. pyogens. Quinupristin should be reserved for the treatment of serious infections caused by multiple drug resistant gram-positive organisms such as vancomycin- resistant E.faecium.
Categories
- 6 Anti-infective drugs
- 6.2 Antibiotics, systemic
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Quinupristin's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| No data regarding the Adult dosage details of Quinupristin is available. |
Paedriatic Dosage (20kg)
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| No data regarding the Paedriatic dosage details of Quinupristin is available. |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Quinupristin is available. |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Quinupristin
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