Ciprofloxacin

Overview

Ciprofloxacin is a fluoroquinolone antimicrobial agent with a broad spectrum of activity against both gram-negative and gram-positive bacteria.They are relatively non-toxic and well tolerated broad spectrum agents. Their excellent bioavailibilty permits their use for treatment of variety of serious bacterial infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Ciprofloxacin (HCl) is important to take the drug for the full time period as prescribed. If you discontinue the therapy it may result in ineffective treatment.
Ciprofloxacin (HCl) is the monohydrated hydrochloride salt of ciprofloxacin. Ciprofloxacin (HCl) is effective against many gram positive and gram negative bacteria, including some strains resistant to penicillins, cyclosporins and aminoglycosides.

Categories

• 6 Anti-infective drugs
  • 6.2 Antibiotics, systemic
    • 6.2.2 Other anti-bacterial drugs
      • 6.2.2.2 Quinolones

• 21 Ophthalmological preparations
  • 21.1 Anti-infectives
  • 21.1.1 Antibacterials

• 28 Otic drugs

Page headings

Primary Characterstics

Indications

Pharmacokinetics

Contraindications

Drug Interactions

Side Effects

Dosage

Ciprofloxacin's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
200 to 400 mg	300 (300)	12 hourly	IV	As required. Usually for 5-7 days.
0.3 %	0.3 (0.3)	6 hourly	Ophthalmic
250 to 750 mg	500 (500)	12 hourly	PO	As required. Single dose for gonorrhea
Paedriatic Dosage (20kg)
No data regarding the Paedriatic dosage details of Ciprofloxacin is available.
Neonatal Dosage (3kg)
No data regarding the neonatal dosage details of Ciprofloxacin is available.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Warning / Precautions

Storage Conditions

Interference in Pathology

• Elevations of SGPT and SGOT
• Serum creatinin raised
• Elevation in ALT or AST
• blood urea raised

Brands / Trade Names of Ciprofloxacin

Click on the desired strength of the dosage form to view its available brands.

Single Ingredient

Inj: 200 mg, 200 mg/100ml, 400 mg/100ml,
Inf: 100 mg/50ml, 100 mg/100ml, 200 mg/100ml, 250 mg/100ml, 400 mg/100ml, 500 mg/100ml,
Eye Drops: 0.3 %w/v,
Ear Drops: 0.3 %w/v,
Eye Oint: 0.3 %w/w,
Syrup: 125 mg/5ml, 250 mg/5ml,
Susp: 125 mg, 250 mg, 125 mg/5ml, 250 mg/5ml, 253 mg/5ml, 500 mg/5ml,
Liniment: 1.5 %w/w,
Tabs: 1 g, 100 mg, 200 mg, 250 mg, 400 mg, 500 mg, 750 mg,
Caps: 250 mg, 500 mg,

Multi ingredient

Drops: 0.3 %w/v,
Eye Drops: 0.3 %w/v,
Ear Drops: 0.3 %w/v,
Caps: 250 mg, 500 mg,

Manufacturers of Ciprofloxacin in Pakistan

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