loteprednol
Overview
loteprednol (as Loteprednol Etabonate) contains a sterile, topical anti-inflammatory corticosteroid for ophthalmic use. Loteprednol etabonate is a white to off white powder.chemically it is chloromethyl 17a-[(ethoxycarbonyl)oxy]-11ß-hydroxy-3-oxoandrosta-1,4-diene-17ß-carboxylate. It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye.
Categories
- 21 Ophthalmological preparations
- 21.2 Anti-inflammatory agents
Primary Characterstics
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Pharmacokinetics
Metabolism is reported extensive.
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Contraindications
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Side Effects
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Dosage
Loteprednol's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 1 to 2 % | 1.5 (1.5) | 6 hourly | opthalmic | Seasonal Allergic Conjunctivitis |
| 1 to 2 % | 1.5 (1.5) | 6 hourly | opthalmic | Inflammatory Ocular Disorders |
| 1 to 2 % | 1.5 (1.5) | 6 hourly | opthalmic | Post Operative Ocular Inflammation |
Paedriatic Dosage (20kg)
|
| No data regarding the Paedriatic dosage details of Loteprednol is available. |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Loteprednol is available. |
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
No data regarding the pathological interferences produced by loteprednol is available.
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Brands / Trade Names of
Loteprednol
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