Severity N/A
Bendrofluazide Interaction of Bendrofluazide with Lithium
Bumetanide Interaction of Bumetanide with Lithium
Chlorothiazide Interaction of Chlorothiazide with Lithium
Chlorpromazine (HCl) Interaction of Chlorpromazine (HCl) with Lithium
Chlortetracycline (HCl) Interaction of Chlortetracycline (HCl) with Lithium
Chlorthalidone Interaction of Chlorthalidone with Lithium
Clopamide Interaction of Clopamide with Lithium
Cyclopenthiazide Interaction of Cyclopenthiazide with Lithium
Demeclocycline (HCl) Interaction of Demeclocycline (HCl) with Lithium
Desipramine (HCl) Interaction of Desipramine (HCl) with Lithium
Desmopressin (Acetate) Interaction of Desmopressin (Acetate) with Lithium
Dexamphetamine (Sulphate) Interaction of Dexamphetamine (Sulphate) with Lithium
Diltiazem (HCl) Interaction of Diltiazem (HCl) with Lithium
Distigmine (Br) Interaction of Distigmine (Br) with Lithium
Doxepin (HCl) Interaction of Doxepin (HCl) with Lithium
Droperidol Interaction of Droperidol with Lithium
Ethacrynic Acid Interaction of Ethacrynic Acid with Lithium
Fluphenazine Interaction of Fluphenazine with Lithium
Human Insulin Interaction of Human Insulin with Lithium
Hydroflumethiazide Interaction of Hydroflumethiazide with Lithium
Iodine Interaction of Iodine with Lithium
Ketoprofen Interaction of Ketoprofen with Lithium
Lisinopril Interaction of Lisinopril with Lithium
Mannitol Interaction of Mannitol with Lithium
Mefruside Interaction of Mefruside with Lithium
Methyclothiazide Interaction of Methyclothiazide with Lithium
Methyldopa Interaction of Methyldopa with Lithium
Metoclopramide (HCl) Interaction of Metoclopramide (HCl) with Lithium
Minocycline (HCl) Interaction of Minocycline (HCl) with Lithium
Naproxen Interaction of Naproxen with Lithium
Neostigmine Interaction of Neostigmine with Lithium
Pancuronium (Br) Interaction of Pancuronium (Br) with Lithium
Polythiazide Interaction of Polythiazide with Lithium
Ramipril Interaction of Ramipril with Lithium
Sodium Bicarbonate Interaction of Sodium Bicarbonate with Lithium
Spectinomycin (HCl) Interaction of Spectinomycin (HCl) with Lithium
Suxamethonium (Cl) Interaction of Suxamethonium (Cl) with Lithium
Tetracycline (HCl) Interaction of Tetracycline (HCl) with Lithium
Theophylline Interaction of Theophylline with Lithium
Ticarcillin (di Na) Interaction of Ticarcillin (di Na) with Lithium
Tienilic Acid Interaction of Tienilic Acid with Lithium
Verapamil (HCl) Interaction of Verapamil (HCl) with Lithium
Cilazapril Interaction of Cilazapril with Lithium
Paroxetine Interaction of Paroxetine with Lithium
Perindopril Interaction of Perindopril with Lithium
Potassium Iodide Interaction of Potassium Iodide with Lithium
Rivastigmine Interaction of Rivastigmine with Lithium
Secnidazole Interaction of Secnidazole with Lithium
Tramadol (HCl) Interaction of Tramadol (HCl) with Lithium
Fosinopril (Na) Interaction of Fosinopril (Na) with Lithium
Ketorolac (Tromethamine) Interaction of Ketorolac (Tromethamine) with Lithium
Sodium Iodide Interaction of Sodium Iodide with Lithium
Oxtriphylline (Choline Theophyllinate) Interaction of Oxtriphylline (Choline Theophyllinate) with Lithium
Bupropion (HCl) Interaction of Bupropion (HCl) with Lithium
Gallopamil Interaction of Gallopamil with Lithium
Lypressin Interaction of Lypressin with Lithium
Vasopressin Interaction of Vasopressin with Lithium
Azapropazone Interaction of Azapropazone with Lithium
Tetrabenazine Interaction of Tetrabenazine with Lithium
Piretanide Interaction of Piretanide with Lithium
Celecoxib Interaction of Celecoxib with Lithium
Insulin Lispro Interaction of Insulin Lispro with Lithium
Sibutramine Interaction of Sibutramine with Lithium
Rubidium Iodide Interaction of Rubidium Iodide with Lithium
Baclofen Interaction of Baclofen with Lithium
Details: Effects of muscle relaxants (e.g Baclofen) enhanced by Lithium; Baclofen possibly aggravates hyperkinesis caused by lithium.
Interaction of Diazepam with Lithium
Details: When both drugs given in combination cause Hypothermia
Interaction of Diclofenac (Na) with Lithium
Details: decrease in plasma concentration of diclofenac by sucralfate
Interaction of Enalapril (Maleate) with Lithium
Details: coadministration may increase lithium plasma level and lithium toxcity occur
Management: lithium levels should be monitored
Interaction of Fluoxetine (HCl) with Lithium
Details: co administration may lead to lithium toxicity, symptomps include agitation, restlessness, GI distress
Management: lithium level should be monitored
Interaction of Hydrochlorothiazide with Lithium
Details: Volume depletion by Hydrochlorothiazide increases lithium absorption and causes Lithium toxicity
Interaction of Metronidazole with Lithium
Details: Lithium toxicity occurs when lithium is used with metronidazole.
Interaction of Nabumetone with Lithium
Details: Nabumetone has produced an elevation of plasma lithium levels and a reduction in renal lithium clearance.
Interaction of Pyridostigmine (Br) with Lithium
Details: lithium interfere with neuromuscular conduction
Interaction of Tiaprofenic Acid with Lithium
Details: Lithium levels can be increased.
Management: Avoid concurrent use if possible or monitor lithium levels and adjust dose.
Interaction of Aescin with Lithium
Rofecoxib Interaction of Rofecoxib with Lithium
Details: Rofecoxib have produced an elevation of plasma lithium levels and a reduction in renal lithium clearance resulting in lithium toxcity.
Interaction of Imidapril with Lithium
Tenoxicam Interaction of Tenoxicam with Lithium
Details: Lithium toxicity may result due to decreased elimination of lithium.
Interaction of Chlorocarbachol with Lithium
Iodide Interaction of Iodide with Lithium
Telmisartan Interaction of Telmisartan with Lithium
Details: Reversible increases in serum lithium concentrations and toxicity have been reported during concomitant administration of lithium with Telmisartan.
Interaction of Moexipril with Lithium
Dexketoprofen Interaction of Dexketoprofen with Lithium
Molindone Interaction of Molindone with Lithium
Details: The risk of certain serious side effects is increased when taken with Molindone.
Interaction of Oxyphenbutazone with Lithium
Details: These drugs should not be taken concurrently with out doctor and pharmacist approval.
Interaction of Salsalate with Lithium
Details: Salsalate may increase the blood levels of lithium by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity.
Interaction of Piroxicam-beta-cyclodextrin with Lithium
Details: Piroxicam decreases renal excretion of lithium
Interaction of Lornoxicam with Lithium
Details: Might lead to an increase of the lithium peak concentration and thus to a possible increase in adverse events.
Management: Monitor lithium serum levels.
Interaction of Dexibuprofen with Lithium
Details: NSAIDs can increase the plasma levels of lithium, by reducing its renal clearance.
Management: The combination is not recommended. Frequent lithium monitoring should be performed. The possibility of reducing the dose of lithium should be considered.
Interaction of Dapoxetine HCl with Lithium
Details: may lead to an incidence of serotonin associated effects.
Management: Dapoxetine should not be used in combination with other SSRIs, MAOIs or
other serotonergic medicinal/herbal products
Interaction of Vortioxetine with Lithium
Details: increases the level of vortioxetine
Management: monitor closely ,use alternative
Moderate
Captopril Interaction of Captopril with Lithium
Details: Captopril may increase the serum concentration of Lithium
Onset: Delayed
Management: Monitor for increased serum concentrations/toxic effects of lithium if Captopril is initiated/dose increased, or decreased effects if Captopril is discontinued/dose decreased. Lithium dosage reductions will likely be needed following the addition of Captopril.
Interaction of Carbamazepine with Lithium
Details: Neurotoxicity,lethargy,muscular weakness,ataxia,dystonia,tremor and sinus node dysfunction may occur when Carbamazepine given with Lithium.
Management: Adverse neurologic and cardiac effects,lithium toxicity and altered thyroxine levels must be monitor.
Interaction of Alcohol with Lithium
Details: Coadministration result in additive central nervous system and impairment, thinking and psychomotor skills.
Management: Patient should be warned of interaction and advised to limit alcohol cosumption.
Interaction of Haloperidol with Lithium
Details: Both of them have been use together safely.Fewer patients may observe encephalopathic syndrome consisting of neurotoxic effect and extra pyramidal symptoms followed by irreversible brain damage.
Management: . Larger doses should be avoided. Mainly reduce the haloperidol dose.During the first week of treatment careful observation should be done and if any sign of encephalopathic syndrome occurs discontinued the treatment.
Interaction of Indomethacin with Lithium
Details: Indomethacin increases the serum concentration of lithium results in increased toxicity.
Management: Closely monitor the serum level of lithium.
Interaction of Clozapine with Lithium
Details: Both agents act as additive serotonergic result in the development of neurologic toxicity.
Management: Closely monitor for neurologic symptoms and check the level of blood glucose regularly.
Interaction of Tubocurarine (Cl) with Lithium
Details: Lithium exacerbate the pharmacological effects of tubocurarineresults in prolonged apnea and delayed recovery from anesthesia.
Management: Closely monitor for respiratory depression and life support should be readily available in case of emergency
Interaction of Losartan (K) with Lithium
Details: Losartan increases the plasma level of lithium by inhibiting secretion of aldosterone result in increased toxicity.
Management: Closely monitor the patient for lithium toxicity.
Interaction of Thioridazine (HCl) with Lithium
Details: Coadministration may initiate the number of neurologic and psychiatric symptoms such as extrapyramidal effects, seizures, change in mental status, delirium, fever etc
Management: Closely monitor the patient for changed efficacy and safety. Discontinue one or both agents if necessary.
Interaction of Doxacurium with Lithium
Details: Llithium potentiate the pharmacological effect of doxacurium.Prolong apnea and delayed recovery from anesthesia occurs when they administered in combination.
Management: Close monitoring for the development of respiratory depression.