Prochlorperazine

Overview

Categories

Primary Characterstics

Molecular Structure of Prochlorperazine

Prochlorperazine is also known as Chlormeprazine, Chlormeprazine.Prochlorperazine is also known as Chlormeprazine, Chlormeprazine. It is of Synthetic origin and belongs to Phenothiazine. It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Antiemetic/Antivertigo Agents and Antipsychotic Agent pharmacological group.The Molecular Weight of Prochlorperazine is 373.90.

Its pKa is 8.1.

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Prochlorperazine's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

5 to 10 mg7.5 (7.5)6 hourlyIMFrequency may be increased uoto 6 times/day if needed.
25 mg25 (25)8 hourlyIntra Rectal
2.5 to 10 mg6.2 (6.25)4 hourlyIVFrequency may be increased uoto 8 times/day if needed.
5 to 10 mg7.5 (7.5)8 hourlyPO

Paedriatic Dosage (20kg)

0.125 to 0.25 mg/kg0.19 (0.1875)8 hourlyIntra MuscularUse with Caution under 10 Kg BW
0.25 mg/kg0.25 (0.25)8 hourlyIntra Rectal-
0.125 to 0.25 mg/kg0.19 (0.1875)8 hourlyOralUse with Caution under 10 Kg BW

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Prochlorperazine is available.

High Risk Groups

Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Prochlorperazine

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Manufacturers of Prochlorperazine in Pakistan

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