Baclofen

Overview

Primary Characterstics

Molecular Structure of Baclofen

It is of Synthetic origin and belongs to Benzenepropanoic acid. It belongs to GABA-B agonist pharmacological group on the basis of mechanism of action and also classified in Muscle Relaxants and Antipsychotic Agent pharmacological group.The Molecular Weight of Baclofen is 232.00.

Its pKa is 3.85, 9.25.

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Baclofen's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage
5 to 30 mg18 (17.5)8 hourlyPOIncrease Dose Gradually. Max. Dose 100 mg/day

Paedriatic Dosage (20kg)
2.5 to 6 mg/kg4.2 (4.25)8 hourlyOralGradually increase the dose

Neonatal Dosage (3kg)
2.5 to 5 mg/kg3.8 (3.75)8 hourlyoralGradually increase the dose

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Baclofen

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Manufacturers of Baclofen in Pakistan

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