Triamterene
Overview
Triamterene is a potassium sparing diuretic, independent of the presence or absence of aldosterone. Triamterene is antihypertensive agent. Chemically Triamterene is 2, 4, 7- triamino-6-phenylpteridine. It inhibits reabsorption of sodium ions in exchange for potassium and hydrogen ion at the site of distal tubules. Triamterene is also used in combination with thiazide diuretic in the management of oedema associated with congestive heart failure, cirrhosis and nephrotic syndrome.
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Triamterene's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 75 to 125 mg | 100 (100) | 12 hourly | PO | Initially for 1 Week |
| 100 mg | 100 (100) | 12 hourly | PO | Maintenance, every alternate day, As Required |
Paedriatic Dosage (20kg)
|
| 1 to 2 mg/kg | 1.5 (1.5) | 12 hourly | Oral | - |
Neonatal Dosage (3kg)
|
| 1 to 2 mg/kg | 1.5 (1.5) | 12 hourly | Oral | - |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Triamterene
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