Pentoxifylline

Overview

Pentoxifylline is a vasodilator, used in the treatment of peripheral vascular disease like intermittant claudication, Raynaud's syndrome. It may be useful in lowering blood sugar level, also reduces blood presure. Caution may be needed if given with antihypertensive or insulin as it may increase their effects

Categories

Primary Characterstics

Indications

Back to top

Pharmacokinetics

Back to top

Contraindications

Back to top

Drug Interactions

Pentoxifylline is known to interact with other drugs, the details of drug interactions is as follows:

Severity N/A

Theophylline

Interaction of Theophylline with Pentoxifylline

Aspirin

Interaction of Aspirin with Pentoxifylline

Meloxicam

Interaction of Meloxicam with Pentoxifylline

Ketorolac (Tromethamine)

Interaction of Ketorolac (Tromethamine) with Pentoxifylline

Insulin Lispro

Interaction of Insulin Lispro with Pentoxifylline

Insulin Glulisine

Interaction of Insulin Glulisine with Pentoxifylline

Details: Pentoxifylline, oral antidiabetic products, pramlintide, ACE inhibitors, fibrates, monoamine oxidase inhibitors, salicylates, and somatostatin analogs, may increase the blood glucose-lowering effect of insulins and therefore increase the risk of hypoglycemia.

These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Back to top

Side Effects

Back to top

Dosage

Pentoxifylline's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage
400 mg400 (400)8 hourlyPO

Paedriatic Dosage (20kg)
Safety not established

Neonatal Dosage (3kg)
Safety not established

High Risk Groups

Back to top

Warning / Precautions

Back to top

Storage Conditions

Back to top

Interference in Pathology

  • Urinary Estimation of Pregnanediol by Gas Chromatographic Assay.

Back to top

Brands / Trade Names of Pentoxifylline

Back to top

Manufacturers of Pentoxifylline in Pakistan

Back to top

Previous Drug Generic - Next Drug Generic


Suggested Pages