Leflunomide

Overview

Leflunomide is used for its immunosuppressant properties, in the treatment of moderate to severe active rheumatoid arthritis and in active psoriatic arthritis. The immunosuppressant properties are partly due to the action of its active metabolite A77-1726 in inhibiting pyrimidine synthesis. Leflunomide is under invastiagation for its use in organ and tissue transplantation.

Categories

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Leflunomide's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

100 mg100 (100)24 hourlyPOFor 3 days. Then 10-20 mg QD for maintenance.

Paedriatic Dosage (20kg)

No data regarding the Paedriatic dosage details of Leflunomide is available.

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Leflunomide is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Leflunomide

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