Histidine

Overview

Amrinone (Lactate) is a vasodilator with positive inotropic properties, belongs to phosphodisterase inhibitors. Amrinone (Lactate) is used for the short term management of heart failure unresponsive to other forms of therapy. The mechanism of action has not been fully determined , however it appears to involve an increase in cAMP concentration due to inhibition of phosphodisterase leading to an increased contractile force in cardiac muscle. Amrinone (Lactate) is given by intravenous route.

Primary Characterstics

Indications

Back to top

Pharmacokinetics

Back to top

Contraindications

Back to top

Drug Interactions

Back to top

Side Effects

The severe or irreversible adverse effects of Amrinone (Lactate), which give rise to further complications include Cardiac arrhythmias, Hepatosplenomegaly, Hypotension, Hepatosplenomegaly.

The signs and symptoms that are produced after the acute overdosage of Amrinone (Lactate) include Thrombocytopenia.

The symptomatic adverse reactions produced by Amrinone (Lactate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Fever, Local pain, Hypersensitivity reactions, Chest pain, GI disturbance, Nail discoloration.

Back to top

Dosage

Histidine's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

250 to 500 mg380 (375)8 hourlyPO

Paedriatic Dosage (20kg)

No data regarding the Paedriatic dosage details of Histidine is available.

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Histidine is available.

High Risk Groups

Back to top

Warning / Precautions

Back to top

Storage Conditions

Back to top

Interference in Pathology

Back to top

Brands / Trade Names of Histidine

Back to top

Manufacturers of Histidine in Pakistan

Back to top

Previous Drug Generic - Next Drug Generic


Suggested Pages