Cisplatin

Overview

Categories

Primary Characterstics

Molecular Structure of Cisplatin

Cisplatin is also known as Cisplatinum, Cisplatinum, Cisplatinum.Cisplatin is also known as Cisplatinum, Cisplatinum, Cisplatinum. It is of Synthetic origin and belongs to Chloroplatinum. It belongs to Cross Linkage (DNA acting) pharmacological group on the basis of mechanism of action and also classified in Antineoplastic Agent, Alkylating Agent pharmacological group.The Molecular Weight of Cisplatin is 300.10.

Its pKa is not relevant.

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Cisplatin's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage
50 to 70 mg/sq.meter60 (60)As recommended.IVadvanced bladder cancer once every 3 to 4 weeks.
75 to 100 mg/sq.meter88 (87.5)As recommended.IVOnce every 4 weeks metastatic ovarian tumors.
15 to 20 mg/ sq.meter/day18 (17.5)As recommended.IV InfFor 5 days every month, As Required. Metastatic testicular tumors.

Paedriatic Dosage (20kg)
32 to 17.5 mg/sq.meter25 (24.75)24 hourly
15 to 20 mg/sq.meter18 (17.5)24 hourlyIntra VenousFor 5 Days, every 3-4 Weeks

Neonatal Dosage (3kg)
No data regarding the neonatal dosage details of Cisplatin is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Cisplatin

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