Danazol
Overview
Danazol is an isoxazole derivative of ethisterone (17a-ethinyl testosterone). It has weak progestational and androgenic activities. It is a synthetic androgen (hormone). itused to treat pain and infertility caused by endometriosis (a condition involving the tissue of the uterus). italso used in the treatment of cysts or lumps in the breast.
Categories
- 18 Hormones and other endocrine drugs and contraceptives
Primary Characterstics
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Pharmacokinetics
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Side Effects
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Dosage
Danazol's dosage details are as follows:
Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
200 to 800 mg | 500 (500) | As recommended. | PO | given in 2 divided doses daily for 3-6months. upto 9 months if necessary. |
Paedriatic Dosage (20kg)
|
10 to 40 | 25 (25) | 24 hourly | Oral | |
Neonatal Dosage (3kg)
|
| | | | Not recommended in this age group |
High Risk Groups
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Warning / Precautions
Danazol should not be used during pregnancy or lactation. It should be usedwith caution in-patients with migraine headaches, heart, liver or kidney disease, a history of seizures, breast cancer, abnormal bleeding, previous strokes, prostate cancer or any other diseases. Extreme caution is advised for use in children. Pediatric specialist consultation is also advised. Geriatric men are at increased risk of developing enlarged prostate and prostate cancer with the use of androgen-like drugs, so use cautiously.
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Storage Conditions
Caps
Store Below 40°C. Protect from Sunlight and Moisture.
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Interference in Pathology
- Interferes with Thyroid Function Test
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Brands / Trade Names of
Danazol
Click on the desired strength of the dosage form to view its available brands.
Single Ingredient
Tabs: 200 mg,
Caps: 100 mg, 200 mg,
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