Eplerenone

Overview

Categories

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Eplerenone's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

25 to 50 mg38 (37.5)24 hourlyPOCHF Post-MI Initial: 25 mg once daily; titrate to recommended dose of 50 mg once daily within 4 wk as tolerated. Adjust dose based on serum potassium level; reduce or withdraw therapy if hyperkalaemia develops
50 to 50 mg50 (50)24 hourlyPOHypertension, Initial with 50 mg once daily; may increase to 50 mg twice daily based on response. Initiate at lower dose of 25 mg once daily if used concurrently with moderate CYP3A4 inhibitors.
50 to 50 mg50 (50)12 hourlyPOHypertension, Initial with 50 mg once daily; may increase to 50 mg twice daily based on response.

Paedriatic Dosage (20kg)

No data regarding the Paedriatic dosage details of Eplerenone is available.

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Eplerenone is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Eplerenone

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Manufacturers of Eplerenone in Pakistan

Macter Platinum Tabros

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