Biphasic insulin
Overview
Biphasic insulins are mixtures of insulin providing for both immediate and prolonged actions. These mixtures form intermediate acting insulins. Usually, Human insulin R is available in combination with NPH or isophane insulin in 30/70 ratio. Other insulins are also available as biphasic insulins for example insulin aspart/insulin aspart protamine, insulin lispro/insulin lispro protamine. Biophasic insulins may be available in 30/70, 50/50, 25/75 ratio. Insulins available in combination can only be used subcutaneously. Combination insulin or Biphasic insulins are not for intravenous use.
Pharmacokinetics of insulin aspart/insulin aspart protamine combination, insulin lispro/insulin lispro protamine combination and soluble human insulin R/isophane insulin combination is different from each other. So, these can be given either once daily, twice daily and thrice daily depending upon the required glycemic control.
Categories
No Categories Defined
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Biphasic insulin's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| No data regarding the Adult dosage details of Biphasic insulin is available. |
Paedriatic Dosage (20kg)
|
| No data regarding the Paedriatic dosage details of Biphasic insulin is available. |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Biphasic insulin is available. |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Biphasic insulin
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Manufacturers of
Biphasic insulin
in Pakistan
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