peginterferon alfa-2b

Overview

Categories

  • 6 Anti-infective drugs
    • 6.5 Antivirals, systemic
  • 6 Anti-infective drugs
    • 6.5 Antivirals, systemic

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Peginterferon alfa-2b's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

1 to 1 mcg/kg/week1 (1)As recommended.ScDose reduction or discontinuation is required in case of depression, haemtological and renal side effects. For patients with a history of stable cardiac disease receiving Pegnterferon alfa 2b in combination with ribavirin, dose should be reduced by half and the ribavirin dose by 200mg/day if a 2g/dL decrease in hemoglobin is observed during any 4 week period. Both Peginterferon alpha 2b and ribavirin should be permanently discontinued if patients have hemoglobin levels <12 g/dL after this ribavirin dose reduction.
1.5 to 1.5 mcg/kg/week1.5 (1.5)As recommended.Scwhen it is used in combination with ribavirin.

Paedriatic Dosage (20kg)

60 to 0 mcg/m2/week30 (30)As recommended.ScThis is the dose when given in combination with ribavirin

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Peginterferon alfa-2b is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Peginterferon alfa-2b

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Manufacturers of peginterferon alfa-2b in Pakistan

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