Diloxanide (Furoate)

Overview

Diloxanide (Furoate) is a dichloroacetamide derivative. It acts as amebicidal agent. Diloxanide (Furoate) is used in the treatment of intestinal amebiasis (dysentery) in combination with other drugs. Diloxanide fucoate is a pcodeng and is hydcolyned in the gut to diloxamide (active ingredient)

Categories

Primary Characterstics

Indications

Diloxanide (Furoate) is primarily indicated in conditions like Asymptomatic cyst passers, Eradication, Intestinal amoebiasis, Mild amebic dysentery, Non-dysenteric intestinal amebiasis, Oliguria due to renal failure, Oliguria due to renal failure, Parkinsonism.

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Diloxanide (Furoate)'s dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

20 to 25 mg/kg22 (22.5)As recommended.May repeat if needed take with food.
500 mg500 (500)8 hourlyPOFor 10 Days

Paedriatic Dosage (20kg)

5 to 10 mg/kg7.5 (7.5)8 hourlyOralRecommended for 5-12 Yrs of Children
20 mg/kg20 (20)As recommended.OralChildren of 12 years. It is given for 10days.

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Diloxanide (Furoate) is available.

High Risk Groups

Drug should not be given to Pregnant Mothers, and Neonates.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Diloxanide (Furoate)

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