Acetylcysteine Overview Categories 4 Antidotes and other substances used in poisonings4.2 Specific antidotes4.2.1 paracetamol overdose 21 Ophthalmological preparations21.7 Other ophthalmologicals 25 Drugs acting on the respiratory tract25.2 Antitussives25.2.2 Expectorants Page headings Overview Primary Characterstics Indications Pharmacokinetics Contraindications Drug Interactions Side Effects Dosage High Risk Groups Warning / Precautions Storage Conditions Interference in Pathology Brands of Acetylcysteine Manufacturers of Acetylcysteine Primary Characterstics Indications Back to top Pharmacokinetics Back to top Contraindications Back to top Drug Interactions Back to top Side Effects Back to top Dosage Acetylcysteine's dosage details are as follows: Dose Single Dose Frequency Route Instructions Adult Dosage 3 to 5 ml4 (4)4 hourlyInhalationAs 20% solution for mucolytic effect inhaled as nebulizer 3-4 times/day.6 to 10 ml8 (8)6 hourlyNebulizer3-5ml of 20% solution as nebulizer for mucolytic effect. 2 Nebulizations in each nostril.OpthalmicFor dry eye associated with abnormal mucus production, acetylcysteine, usually as a 5% solution with hypromellose, is given topically 3 or 4 times daily.140 to 140 mg/Kg140 (140)As recommended.POThis is an initial dose for Paracetamol poisning. Give 140mg/Kg as 5% solution.70 to 70 mg/Kg70 (70)4 hourlyPOFor Paracetamol poisning: Give 17 doses of 70mg/Kg after initial dose with an interval of 4 hours.600 to 600 mg600 (600)As recommended.POAs mucolytic in usual dose of 600 mg daily as a single dose or in three divided doses. Paedriatic Dosage (20kg) 0.125 mg/kg.min0.12 (0.125)As recommended.IV InfusionMaintenance for 20 Hours, As Required10 mg/kg.min10 (10)As recommended.IV InfusionInitially for 15 Minutes2 to 3 gm2.5 (2.5)12 hourlyPO Neonatal Dosage (3kg) 0.125 mg/kg/min0.12 (0.125)As recommended.InfusionMaintenance, over 20 hrs., As required10 mg/kg/min10 (10)As recommended.InfusionInitial , For 15 minutes High Risk Groups Back to top Warning / Precautions Back to top Storage Conditions Back to top Interference in Pathology Back to top Brands / Trade Names of Acetylcysteine Back to top Manufacturers of Acetylcysteine in Pakistan Abbott GSK Mac & Rans Scharper Shrooq Usmanco Back to top Previous Drug Generic - Next Drug Generic