Acetylcysteine

Overview

Categories

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Acetylcysteine's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

3 to 5 ml4 (4)4 hourlyInhalationAs 20% solution for mucolytic effect inhaled as nebulizer 3-4 times/day.
6 to 10 ml8 (8)6 hourlyNebulizer3-5ml of 20% solution as nebulizer for mucolytic effect. 2 Nebulizations in each nostril.
OpthalmicFor dry eye associated with abnormal mucus production, acetylcysteine, usually as a 5% solution with hypromellose, is given topically 3 or 4 times daily.
140 to 140 mg/Kg140 (140)As recommended.POThis is an initial dose for Paracetamol poisning. Give 140mg/Kg as 5% solution.
70 to 70 mg/Kg70 (70)4 hourlyPOFor Paracetamol poisning: Give 17 doses of 70mg/Kg after initial dose with an interval of 4 hours.
600 to 600 mg600 (600)As recommended.POAs mucolytic in usual dose of 600 mg daily as a single dose or in three divided doses.

Paedriatic Dosage (20kg)

0.125 mg/kg.min0.12 (0.125)As recommended.IV InfusionMaintenance for 20 Hours, As Required
10 mg/kg.min10 (10)As recommended.IV InfusionInitially for 15 Minutes
2 to 3 gm2.5 (2.5)12 hourlyPO

Neonatal Dosage (3kg)

0.125 mg/kg/min0.12 (0.125)As recommended.InfusionMaintenance, over 20 hrs., As required
10 mg/kg/min10 (10)As recommended.InfusionInitial , For 15 minutes

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Acetylcysteine

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Manufacturers of Acetylcysteine in Pakistan

Abbott GSK Mac & Rans Scharper Shrooq Usmanco

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