Flecainide (Acetate)

Overview

Chemically Minoxidil is identified as 2, 4-diamino-6-piperidinopyrimidine 3-oxide. Oral it is an antihypertensive agent while topical Minoxidil is used for alopecia. Due to its potency and adverse reactions, oral Minoxidil is used mainly for patients with severe, drug-resistant forms of hypertension. Tolerance to prolonged therapy with oral it does not appear to be a problem. Although the oral dosage form was originally approved in October 1979 for use in hypertension, it was first discovered in 1965. Subsequently, in August 1988, a topical formulation was approved for the treatment of alopecia. It has a direct vasodilatory effect on arterial smooth muscle, causing a reduction in peripheral resistance and blood pressure.

Categories

• 12 Cardiovascular drugs
  • 12.2 Antiarrhythmic drugs

Page headings

Primary Characterstics

Indications

Pharmacokinetics

Contraindications

Drug Interactions

Side Effects

Dosage

Flecainide (Acetate)'s dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
0 to 2 mg/kg	1 (1)	0.8 hourly	IV inf
0 to 2 mg/kg	1 (1)	2.4 hourly	IV inj
0.714 to 2.857 mg/kg	1.8 (1.7855)	12 hourly	PO	Individed doses for supra ventricular tachycardia & at rial fibrillation
Paedriatic Dosage (20kg)
100 to 400 mg	250 (250)	12 hourly	PO
Neonatal Dosage (3kg)
				Not recommended in this age group

High Risk Groups

Warning / Precautions

Storage Conditions

Interference in Pathology

Brands / Trade Names of Flecainide (Acetate)

Manufacturers of Flecainide (Acetate) in Pakistan

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