Folinic Acid Overview Folinic Acid is the 5-formyl derivative of tetrahydrofolic acid. It can act as a co-enzyme carrier in certain folate mediated reactions. Folinic Acid is used as an antidote of antifolate cytotoxic agents and to treat megaloblastic anemia. Categories 4 Antidotes and other substances used in poisonings4.2 Specific antidotes4.2.11 Miscellaneous Page headings Overview Primary Characterstics Indications Pharmacokinetics Contraindications Drug Interactions Side Effects Dosage High Risk Groups Warning / Precautions Storage Conditions Interference in Pathology Brands of Folinic Acid Manufacturers of Folinic Acid Primary Characterstics It is of Synthetic origin and belongs to water soluble vitamin. It belongs to Hematological Agents and Antidotes pharmacological group.The Molecular Weight of Folinic Acid is 473.40.Its pKa is 3.1, 4.8, 10.4. Indications Back to top Pharmacokinetics Back to top Contraindications Back to top Drug Interactions Folinic Acid is known to interact with other drugs, the details of drug interactions is as follows:Severity N/AFluorouracil Interaction of Fluorouracil with Folinic AcidMethotrexate Interaction of Methotrexate with Folinic Acid These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. Back to top Side Effects Back to top Dosage Folinic Acid's dosage details are as follows: Dose Single Dose Frequency Route Instructions Adult Dosage 120 mg120 (120)As recommended.IV,IMIn div.doses over 12-24 hrs. Paedriatic Dosage (20kg) No data regarding the Paedriatic dosage details of Folinic Acid is available. Neonatal Dosage (3kg) No data regarding the neonatal dosage details of Folinic Acid is available. High Risk Groups Back to top Warning / Precautions Back to top Storage Conditions Back to top Interference in Pathology Back to top Brands / Trade Names of Folinic Acid Back to top Manufacturers of Folinic Acid in Pakistan Abbott Al-Habib Alina Atco Neo Pharmevo Polyfine PPP Tread Turner Back to top Previous Drug Generic - Next Drug Generic
Folinic Acid Overview Folinic Acid is the 5-formyl derivative of tetrahydrofolic acid. It can act as a co-enzyme carrier in certain folate mediated reactions. Folinic Acid is used as an antidote of antifolate cytotoxic agents and to treat megaloblastic anemia. Categories 4 Antidotes and other substances used in poisonings4.2 Specific antidotes4.2.11 Miscellaneous Page headings Overview Primary Characterstics Indications Pharmacokinetics Contraindications Drug Interactions Side Effects Dosage High Risk Groups Warning / Precautions Storage Conditions Interference in Pathology Brands of Folinic Acid Manufacturers of Folinic Acid Primary Characterstics It is of Synthetic origin and belongs to water soluble vitamin. It belongs to Hematological Agents and Antidotes pharmacological group.The Molecular Weight of Folinic Acid is 473.40.Its pKa is 3.1, 4.8, 10.4. Indications Back to top Pharmacokinetics Back to top Contraindications Back to top Drug Interactions Folinic Acid is known to interact with other drugs, the details of drug interactions is as follows:Severity N/AFluorouracil Interaction of Fluorouracil with Folinic AcidMethotrexate Interaction of Methotrexate with Folinic Acid These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. Back to top Side Effects Back to top Dosage Folinic Acid's dosage details are as follows: Dose Single Dose Frequency Route Instructions Adult Dosage 120 mg120 (120)As recommended.IV,IMIn div.doses over 12-24 hrs. Paedriatic Dosage (20kg) No data regarding the Paedriatic dosage details of Folinic Acid is available. Neonatal Dosage (3kg) No data regarding the neonatal dosage details of Folinic Acid is available. High Risk Groups Back to top Warning / Precautions Back to top Storage Conditions Back to top Interference in Pathology Back to top Brands / Trade Names of Folinic Acid Back to top Manufacturers of Folinic Acid in Pakistan Abbott Al-Habib Alina Atco Neo Pharmevo Polyfine PPP Tread Turner Back to top Previous Drug Generic - Next Drug Generic