Imipramine (HCl)
Overview
Imipramine (HCl) was recognized as an antidepressant in 1950s and is the prototype drug of tricyclic antidepressants of the class dibenzazepine class. Tricyclic antidepressant is used for almost four decades. Chemically itclosely related to the phenothiazines. itthe first of the tricyclic antidepressants to be used. Imipramine (HCl) has characteristic three ring nucleus. itprepared by chemical synthesis. italso used in the treatment of childhood enuresis, anxiety in panic syndrome, and chronic pain.
Categories
- 24 Psychotherapeutic drugs
- 24.2 Drugs used in mood disorders
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Imipramine (HCl)'s dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 50 to 100 mg | 75 (75) | As recommended. | | A single dose at bed time, usual maintanace. |
| 75 mg | 75 (75) | 24 hourly | PO | Gradually increased to 150 to 200mg |
Paedriatic Dosage (20kg)
|
| 25 mg | 25 (25) | As recommended. | | For children 6 to 7 years (20-25kg) |
| 50 | 50 (50) | As recommended. | | For children aged 8 to 11 years (25-35kg) |
| 1 to 2 mg/kg | 1.5 (1.5) | 24 hourly | Oral | Recommended for 5-12 Years Children at Bed Time |
Neonatal Dosage (3kg)
|
| | | | Not recommended in this age group |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Imipramine (HCl)
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Manufacturers of
Imipramine (HCl)
in Pakistan
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