| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 10 to 10 mg | 10 (10) | As recommended. | IV | This is the dose for pulmonary embolism. Give this initial IV dose over 1-2 minutes. This dose should be followed by 90mg by intravenous infusion over 2 hours, maximum 1.5 mg/Kg in patients less than 65 Kg. |
| 15 to 15 mg | 15 (15) | As recommended. | IV | This is the accelerated regimen for myocardial infarction. Initiate within 6 hours of symptom onset. This dose should be followed by 50mg by intravenous infusion over 30 minutes, then 35 mg over 60 minutes (total 100 mg over 90 minutes). |
| 15 to 15 mg | 15 (15) | As recommended. | IV | This is the accelerated regimen for myocardial infarction for patients less then 65 Kg weight. This dose should be followed by 0.75mg/Kg by intravenous infusion over 30 minutes, then 0.5mg/Kg over 60 minutes (total 100 mg over 90 minutes). |
| 10 to 10 mg | 10 (10) | As recommended. | IV | This is for myocardial infarction within 6-12 hours of symptom onset. This dose should be followed by 50mg by intravenous infusion over 60 minutes, then 4 infusions each of 10mg over 30 minutes (total 100 mg over 3 hours; maximum 1.5 mg/Kg in patients less than 65 Kg). |
| 900 to 900 mcg/Kg | 900 (900) | As recommended. | IV | This is the dose for acute stroke initiate within 4.5 hours of symptom onset. Infuse over 60 minutes (Maximum 90 mg); initial 10% dose by intraveous injection, remainder by IV infusion. |
Paedriatic Dosage (20kg)
|
| 0.75 mg/kg | 0.75 (0.75) | As recommended. | Intra Venous | As Required |
| 100 to 500 mcg/kg.hour | 300 (300) | As recommended. | IV-Inf | For 3-6 hours; maximum 100 mg total daily dose; use ultrasound assessment to monitor effect before c |
Neonatal Dosage (3kg)
|
| 100 to 500 mg/kg/hour | 300 (300) | As recommended. | IV-Inf | It can be given for 3-6 hours and ultrasound assessment to moniter effect before considering a second cause of treatment. |