Lignocaine
Overview
Lignocaine is a sodium channel blocking agent, used as a local anesthetic and antiarrhythmic agent. It stabilizes nerve cell membranes to prevent impulse conduction. Used topically or by injection for local anaesthesia in minor operations.Intravenous injection or infusion used to treat abnormal heart rhythms. Excessive doses also block motor impulses and normal cardiac conduction. It has a low incidence of toxicity and a high degree of effeciveness in arrhythmias. Lignocaine is one of the least cardiotoxic drug of the currently used sodium channel blocker.
Categories
- 1 Drugs used in anesthesia
Primary Characterstics
Benperidol is also known as Benzperidol.Benperidol is also known as Benzperidol. It is of Synthetic origin and belongs to Benzimidazole. It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Antipsychotic Agent pharmacological group.The Molecular Weight of Benperidol is 381.50.
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Lignocaine's dosage details are as follows:
Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
50 to 300 mg | 180 (175) | As recommended. | IV Inf | Max of 4mg/kg |
50 to 100 mg | 75 (75) | As recommended. | IV Inj | For ventricular arrythmias. |
4.5 mg/ kg /dose | 4.5 (4.5) | As recommended. | SC | Dose vary with procedure. do not repeat within two hours. |
1 to 2 % | 1.5 (1.5) | 3 hourly | Topical | As Required |
5 % | 5 (5) | As recommended. | Topical | For spinal Anestheria as hyperbaric. |
Paedriatic Dosage (20kg)
|
20 to 50 ug/kg.min | 35 (35) | As recommended. | IV Infusion | Maintenance, As Required |
0.5 to 1 mg/kg | 0.75 (0.75) | As recommended. | Slow IV | Initially, As Required |
2 % | 2 (2) | 3 hourly | Topical | As Required |
Neonatal Dosage (3kg)
|
20 to 50 ug/kg.min | 35 (35) | As recommended. | IV Infusion | Maintenance, As Required |
0.5 to 1 mg/kg | 0.75 (0.75) | As recommended. | Slow IV | Initially, As Required |
2 % | 2 (2) | 3 hourly | Topical | As Required |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Lignocaine
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