Lignocaine

Overview

Lignocaine is a sodium channel blocking agent, used as a local anesthetic and antiarrhythmic agent. It stabilizes nerve cell membranes to prevent impulse conduction. Used topically or by injection for local anaesthesia in minor operations.Intravenous injection or infusion used to treat abnormal heart rhythms. Excessive doses also block motor impulses and normal cardiac conduction. It has a low incidence of toxicity and a high degree of effeciveness in arrhythmias. Lignocaine is one of the least cardiotoxic drug of the currently used sodium channel blocker.

Categories

Primary Characterstics

Benperidol is also known as Benzperidol.Benperidol is also known as Benzperidol. It is of Synthetic origin and belongs to Benzimidazole. It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Antipsychotic Agent pharmacological group.The Molecular Weight of Benperidol is 381.50.

Indications

Back to top

Pharmacokinetics

Back to top

Contraindications

Back to top

Drug Interactions

Back to top

Side Effects

Back to top

Dosage

Lignocaine's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

50 to 300 mg180 (175)As recommended.IV InfMax of 4mg/kg
50 to 100 mg75 (75)As recommended.IV InjFor ventricular arrythmias.
4.5 mg/ kg /dose4.5 (4.5)As recommended.SCDose vary with procedure. do not repeat within two hours.
1 to 2 %1.5 (1.5)3 hourlyTopicalAs Required
5 %5 (5)As recommended.TopicalFor spinal Anestheria as hyperbaric.

Paedriatic Dosage (20kg)

20 to 50 ug/kg.min35 (35)As recommended.IV InfusionMaintenance, As Required
0.5 to 1 mg/kg0.75 (0.75)As recommended.Slow IVInitially, As Required
2 %2 (2)3 hourlyTopicalAs Required

Neonatal Dosage (3kg)

20 to 50 ug/kg.min35 (35)As recommended.IV InfusionMaintenance, As Required
0.5 to 1 mg/kg0.75 (0.75)As recommended.Slow IVInitially, As Required
2 %2 (2)3 hourlyTopicalAs Required

High Risk Groups

Back to top

Warning / Precautions

Back to top

Storage Conditions

Back to top

Interference in Pathology

Back to top

Brands / Trade Names of Lignocaine

Back to top

Previous Drug Generic - Next Drug Generic


Suggested Pages