Mesalazine
Overview
Bactericidal aminoglycoside antibiotic (the aminoglycosides are the compound containing characteristic amino sugars joined to a hexose nucleus in glycoside linkage, they are polycations and their polarity accounts for their pharmakokinetic peoperties). Kanamycin (Acid Sulphate) is derived from Streptomyces kanamyceticus, consisting of three components designated A, B and C. The clinically active form is a mixture of kanamycins A and B. Kanamycin has actions and spectrum similar to Neomycin, but less ototoxic. Used in gram -ve speticaemia, with monitoring of blood levels, perticularly in renal failure. Kanamycin (Acid Sulphate) is most often applied topically.
Categories
- 17 Gastrointestinal drugs
Primary Characterstics
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Pharmacokinetics
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Side Effects
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Dosage
Kanamycin (Acid Sulphate)'s dosage details are as follows:
Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
800 mg | 800 (800) | 8 hourly | PO | |
1 g | 1 (1) | As recommended. | Rectal(enema) | |
0.5 to 1.5 g | 1 (1) | As recommended. | Rectal(Supostories) | |
Paedriatic Dosage (20kg)
|
10 mg/kg | 10 (10) | 8 hourly | | Maintanance ,To maximum of 500mg |
15 to 0 mg/kg | 7.5 (7.5) | 8 hourly | | For acute attacks (maximum 1g) |
Neonatal Dosage (3kg)
|
| | | | Not recommended in this age group |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Kanamycin (Acid Sulphate)
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