Methotrexate

Overview

Categories

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Methotrexate's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

0.625 to 2.5 mg/kg1.6 (1.5625)As recommended.Lymphosarconas.
7.5 mg7.5 (7.5)As recommended.For Rheumatoid artheitis once weekly.
12 mg/sq.meter22 (22)As recommended.Intra ThecalOnce a week
2.5 mg/kg2.5 (2.5)24 hourlyIVIn leukemia every 14 days.
10 to 25 mg/m218 (17.5)As recommended.POBreast cancer
10 to 25 mg18 (17.5)As recommended.POPsoriasis (once a week)
15 to 30 mg22 (22.5)24 hourlyPO,IMFor 5 days in prophylaxis of choriocarcinoma.

Paedriatic Dosage (20kg)

5 to 15 mg/sq.meter10 (10)As recommended.Intra MuscularPer Week for Rheum. Arthritis
200 mg/sq.meter370 (367)As recommended.Intra VenousFor Induction
1200 mg/sq.meter2200 (2199)As recommended.IV InfusionMaintenance, Over 24 Hours
5 to 15 mg/sq.meter10 (10)As recommended.OralPer Week for Rheum. Arthritis

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Methotrexate is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Methotrexate

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