Pethidine (HCl)

Overview

Categories

Primary Characterstics

Molecular Structure of Pethidine (HCl)

Pethidine (HCl) is also known as Meperidine.Pethidine (HCl) is also known as Meperidine. It is of Synthetic origin. It belongs to OPIATE agonist pharmacological group on the basis of mechanism of action and also classified in Analgesics and Anti-inflammatory Agents pharmacological group.The Molecular Weight of Pethidine (HCl) is 247.33.

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

Pethidine (HCl) is known to interact with other drugs, the details of drug interactions is as follows:

Severity N/A

Disulfiram

Interaction of Disulfiram with Pethidine (HCl)

Etomidate

Interaction of Etomidate with Pethidine (HCl)

Iotroxate (Meglumine)

Interaction of Iotroxate (Meglumine) with Pethidine (HCl)

Methadone

Interaction of Methadone with Pethidine (HCl)

Nitrous Oxide

Interaction of Nitrous Oxide with Pethidine (HCl)

Perphenazine

Interaction of Perphenazine with Pethidine (HCl)

Chlorpromazine (HCl)

Interaction of Chlorpromazine (HCl) with Pethidine (HCl)

Cimetidine (HCl)

Interaction of Cimetidine (HCl) with Pethidine (HCl)

Phenobarbitone

Interaction of Phenobarbitone with Pethidine (HCl)

Phenytoin (Na)

Interaction of Phenytoin (Na) with Pethidine (HCl)

Thiopentone (Na)

Interaction of Thiopentone (Na) with Pethidine (HCl)

Alcohol

Interaction of Alcohol with Pethidine (HCl)

Prazepam

Interaction of Prazepam with Pethidine (HCl)

Promethazine (HCl)

Interaction of Promethazine (HCl) with Pethidine (HCl)

Bromazepam

Interaction of Bromazepam with Pethidine (HCl)

Butorphanol (Tartrate)

Interaction of Butorphanol (Tartrate) with Pethidine (HCl)

Selegiline (HCl)

Interaction of Selegiline (HCl) with Pethidine (HCl)

Fosphenytoin

Interaction of Fosphenytoin with Pethidine (HCl)

Ritonavir

Interaction of Ritonavir with Pethidine (HCl)

Sibutramine

Interaction of Sibutramine with Pethidine (HCl)

Technetium Tc-99m Oxidronate

Interaction of Technetium Tc-99m Oxidronate with Pethidine (HCl)

Details: Possible accumulation of technetium Tc 99m oxidronate at site[s] of injection of Pethidine (HCl).

These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

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Side Effects

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Dosage

Pethidine (HCl)'s dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

50 to 100 mg75 (75)4 hourlyIM,SC

Paedriatic Dosage (20kg)

0.5 to 0.2 mg/kg0.35 (0.35)4 hourlyIntra Muscular-
0.5 to 2 mg/kg1.2 (1.25)4 hourlyOral

Neonatal Dosage (3kg)

1 to 2 1.5 (1.5)4 hourlyIntramuscular

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Pethidine (HCl)

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Manufacturers of Pethidine (HCl) in Pakistan

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