Sulphadiazine

Overview

Sulphadiazine's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
0.5 to 1 g	0.75 (0.75)	6 hourly	PO	In Conjuction with pyrimethamine 25mg/day and with suplemental folinic acid. Doses could be given 2-4g/day in 3-6 divided doses.
Paedriatic Dosage (20kg)
25 mg/kg	25 (25)	6 hourly	Oral	Maintenance after 2 day IV maintenance doses
37.5 mg/kg	38 (37.5)	6 hourly	Oral
25 mg/kg	25 (25)	6 hourly	Slow IV	Maintenance for 2 Days
50 mg/kg	50 (50)	6 hourly	Slow IV	Initial
Neonatal Dosage (3kg)
25 mg/kg	25 (25)	6 hourly	Oral	Maintenance after 2 day IV maintenance doses
37.5 mg/kg	38 (37.5)	6 hourly	Oral
25 mg/kg	25 (25)	6 hourly	Slow IV	Maintenance for 2 Days
50 mg/kg	50 (50)	6 hourly	Slow IV	Initial