Sickle cell anaemia

Anemia characterized by sickle shaped erythrocytes, in these cells, substitution of a single aminoacid takes place (i.e.valine for glutamic acid) at sixth position of beta chain of hemoglobin.result in increased hemolysis leads to decreased number of RBC`s .

 

Medications (drug generics) used in Sickle cell anaemia

Primary Drugs

Azacitidine
Hydroxyurea

Secondary Drugs

Contra Drugs

Cyproterone (Acetate)
Desogestrel
Meglumine
Mestranol
Stilboestrol