Cytarabine (HCl)

Overview

Categories

Primary Characterstics

Indications

Cytarabine (HCl) is primarily indicated in conditions like Acute granulocytic leukemia, Acute leukemia, Acute lymphocytic leukemia, Glioma, Lung cancer and pancreatic cancer, Mesothelioma, Non-hodgkin's lymphoma, Non-hodgkin's lymphoma, Ovarian cancer.

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Cytarabine (HCl)'s dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

100 mg/sq.meter180 (183)As recommended.IV InfFor 5 days. Repeated every 2 weeks total 12 doses

Paedriatic Dosage (20kg)

70 to 200 mg/sq.meter140 (135)24 hourlyIntra VenousMaintenance for 2-5 days per month
200 mg/sq.meter370 (367)24 hourlyIntra VenousInitially for 5 days for induction per 2 weeks

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Cytarabine (HCl) is available.

High Risk Groups

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Warning / Precautions

Cytarabine should be used with caution and in low doses in patients with impaired liver, kidneys or with pre-existing drug induced bone marrow suppression. It is not recommended for use in pregnant or nursing women.

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Cytarabine (HCl)

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Manufacturers of Cytarabine (HCl) in Pakistan

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