Gentamicin

Overview

Categories

Primary Characterstics

Indications

Gentamicin is primarily indicated in conditions like Acute diarrhoea, Bacterial infections, Biliary tract infections, Endocarditis, Food allergy, Muscle relaxation (intermediate duration) during intensive care, Muscle relaxation (intermediate duration) for surgery or intubation, Muscle relaxation (long duration) during intensive care, Pneumonia in hospital patients, Septicaemia, Ulcerative colitis and crohn's disease, Urinary tract infection, and can also be given in adjunctive therapy as an alternative drug of choice in Solid tumor.

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Gentamicin's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

120 mg120 (120)As recommended.For prophylaxis in high risk patients before induction of anaesthesia
160 mg160 (160)As recommended.For urinary tract infections, if renal function is not impaired.
4 to 8 mg6 (6)As recommended.Intra ThecalAs Required
3 to 5 mg/kg4 (4)As recommended.IV,IMIn 3-4 divided doses for 7-10 days. Doses vary according to indication.
0.3 %0.3 (0.3)As recommended.Optical
1 mg/kg/d1 (1)6 hourlyOtic1-2 drops
1 mg/kg/dose1 (1)8 hourlyPOFor prevention of becterial endocarditis. NOT to exceed 80 mg with ampicillin (1-2g). 30 minutes prior to procedures.
0.1 %0.1 (0.1)8 hourlyTopicalOr twice a day if needed.

Paedriatic Dosage (20kg)

0.3 %0.3 (0.3)6 hourlyEar-
2 to 1.5 mg/kg1.8 (1.75)8 hourlyIntra Muscular
2.5 mg/kg2.5 (2.5)8 hourlyIntra Venous-
0.3 %0.3 (0.3)6 hourlyOpthalmic-
0.3 %0.3 (0.3)6 hourlyTopical-

Neonatal Dosage (3kg)

2.5 mg/kg2.5 (2.5)8 hourlyIntramuscular
2.5 mg/kg2.5 (2.5)8 hourlyIntravenous
0.3 %0.3 (0.3)6 hourlyTopical

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Gentamicin

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