Levonorgestrel

Overview

Levonorgestrel is a sex hormone with actions, uses similar to progesterone.. its (-) isomer is used clinically. Chemically Levonorgestrel is identified as 13-ethyl-17-hydroxy-18, 19-dinorpregn-4-en-20-yn-3-one. Levonorgestrel is pricipally used in combination with synthetic estrogen etinyl estadiol for contraception. It can also be used topically through an intrauterine contraceptive device.

Categories

Primary Characterstics

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

The severe or irreversible adverse effects of Levonorgestrel, which give rise to further complications include Malignant hypertension.

Levonorgestrel produces potentially life-threatening effects which include Venous thromboembolism, Ischemic heart disease, Cerebrovascular disease, Venous thromboembolism, Cerebrovascular disease. which are responsible for the discontinuation of Levonorgestrel therapy.

The symptomatic adverse reactions produced by Levonorgestrel are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Nausea, Vomiting, Anxiety, Weight gain, Breast tension, Depressive moods, Changes in libido, Menstrual irregularity, Abdominal discomfort, Uterine bleeding, dizziness, changes in libido.

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Dosage

Levonorgestrel's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

0.75 mg0.75 (0.75)24 hourlyPO

Paedriatic Dosage (20kg)

No data regarding the Paedriatic dosage details of Levonorgestrel is available.

Neonatal Dosage (3kg)

No data regarding the neonatal dosage details of Levonorgestrel is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

Tab

Store Below 40°C. Protect from Sunlight and Moisture.

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Interference in Pathology

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Brands / Trade Names of Levonorgestrel

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Manufacturers of Levonorgestrel in Pakistan

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