Norethisterone

Overview

This belongs to the group of medicines known as progestogens. Norethisterone and its acetate and enantate esters are progestogens derived from nortestosterone that have weak oestrogenic and androgenic properties. They are commonly used as hormonal contraceptives. Norethisterone (Acetate, Heptanoate) was the first highly active oral progestational agent to be synthesized and to achieved widespread use. It was patented in 1951. it is prepared by chemical synthesis from precursors obtained from the Mexican yam. it is available in combination preparations. Chemically it(17a)-17-hydroxy-19-norpregn-4-en-20-yn-3-one. Norethisterone acetate is administered orally and Norethisterone enanthate is administered intramuscularly. itused for contraception and for the treatment of uterine bleeding.

Categories

• 18 Hormones and other endocrine drugs and contraceptives
  • 18.3 Contraceptives
  • 18.3.1 Hormonal contraceptives

Page headings

Primary Characterstics

Indications

Pharmacokinetics

Contraindications

Drug Interactions

Side Effects

Dosage

Co-Trimoxazole's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
200 mg	200 (200)	As recommended.	IM	This dose provide contraception for 8 weeks. The dose is for Norethisterone Enanthate.
15 mg	15 (15)	As recommended.	Oral	Premenstrual syndrome
60 mg	60 (60)	As recommended.	Oral	In Breast cancer
700 mg	700 (700)	As recommended.	Oral	Menopausal HRT
2.5 to 10 mg	6.2 (6.25)	24 hourly	PO	As Required. This dose is for Norethisterone (Acetate, Heptanoate).
Paedriatic Dosage (20kg)
No data regarding the Paedriatic dosage details of Co-Trimoxazole is available.
Neonatal Dosage (3kg)
No data regarding the neonatal dosage details of Co-Trimoxazole is available.

High Risk Groups

Warning / Precautions

Storage Conditions

Tab

Store in a well closed container, Below 40°C.

Interference in Pathology

Brands / Trade Names of Co-Trimoxazole

Manufacturers of Norethisterone in Pakistan

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