Oxaprozin
Overview
Oxaprozin is NSAID (non steroidal antinflammatory drug). Oxaprozin is one of the newest of the propionic acid derivative. It relieves pain and reduces inflammation and fever. It has a very long half life and it can be given once a day. Because of this long half life dose adjustment should be made at intervals no shorter than five days to two weeks.
Categories
- 2 Analgesics, antipyretics, NSAIDs, antigout, and antirheumatics
- 2.1 Non-opioid analgesics
Primary Characterstics
Indications
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Pharmacokinetics
Plasma protien binding is > 99 %. and metabolism is reported Hepatic. Renal Excretion accounts for 65 % and plasma half life is 40 - 50 hr.
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Contraindications
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Side Effects
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Dosage
Oxaprozin's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 600 mg | 600 (600) | 24 hourly | PO | |
Paedriatic Dosage (20kg)
|
| | | | Not recommended for this age group |
Neonatal Dosage (3kg)
|
| | | | Not recommended in this age group |
High Risk Groups
Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Oxaprozin
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