Benzhexol (HCl)
Overview
Chlorpromazine (HCl) is the hydrochloride salt of chlorpromazine which is a phenothiazine derivative. It is used as an antiemetic, antipsychotic and tranquilizer. Chlorpromazine (HCl) is administered by rectal suppositories.
Categories
- 17 Gastrointestinal drugs
Primary Characterstics
Indications
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Pharmacokinetics
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Side Effects
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Dosage
Benzhexol (HCl)'s dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 1 to 2 mg daily | 1.5 (1.5) | 24 hourly | PO | Trihexyphenidyl HCl in Idiopathic Parkinsonism:1mg is administered on first day and then increased by 2mg increments at intervals of three to five days, until a total of 6 to 10 mg is given daily. The total daily dose will depend upon what is found to be the optimal level. Many patients derive maximum benefit from this daily total of 6 to 10 mg, but some patients, chiefly those in the post-encephalitic group, may require a total daily dose of 12 to 15 mg. |
| 5 to 15 mg daily | 10 (10) | 24 hourly | PO | Trihexyphenidyl HCl in Drug-Induced Parkinsonism:It may be advisable to commence therapy with a single 1 mg dose. If the extrapyramidal manifestations are not controlled in a few hours, the subsequent doses may be progressively increased until satisfactory control is achieved. |
Paedriatic Dosage (20kg)
|
| 0.16 mg/kg | 0.16 (0.16) | 24 hourly | Oral | Not recommended under 3 yrs. Dose for 5-12 Yrs of Children |
Neonatal Dosage (3kg)
|
| | | | Not recommended under 3 yrs. |
High Risk Groups
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Warning / Precautions
Chlorpromazine should be used with caution in patients exposed to extreme heat or phosphorus insecticides, patients in state of alcohol withdrawal, patients with history of peptic ulcer, allergic reactions, with renal impairment, prostatic hypertrophy. Photosensitization may occur, caution patients to take appropriate measures (e.g.wear protective clothing or sunscreen) against exposure to sunlight or ultra violet light. Discontinue use atleast 48 hours before myelography.
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Benzhexol (HCl)
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Manufacturers of
Benzhexol (HCl)
in Pakistan
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