Cephalexin (Monohydrate)
Overview
Cephalexin is a first generation cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminocephalosporic acid and are closely related to penicillin in structure. Cephalosporins have a six membered sulfur containing ring adjoining a ß lactam ring. Cephalexin is very active against gram positive cocci and used in a large variety of bacterial infections, such as respiratory tract, skin and urinary tract infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Cephalexin (Monohydrate) is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.
Categories
- 6 Anti-infective drugs
- 6.2 Antibiotics, systemic
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Cephalexin (Monohydrate)'s dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 4 to 8 g | 6 (6) | 8 hourly | IV | For sever infections. Frequency may be increased to 4 times/day if needed. |
| 125 g | 120 (125) | As recommended. | PO | Given at night for prophylaxis of urinary -tract infections. |
| 1 to 2 g | 1.5 (1.5) | 8 hourly | PO,IV | |
Paedriatic Dosage (20kg)
|
| 25 to 100 mg/kg | 62 (62.5) | 12 hourly | Oral | For 5-12 Yrs of Children. To maximum of 4g individed doses. |
Neonatal Dosage (3kg)
|
| 7.812 mg/kg | 7.8 (7.812) | 8 hourly | oral | |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Cephalexin (Monohydrate)
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Manufacturers of
Cephalexin (Monohydrate)
in Pakistan
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