Chloroquine

Overview

Categories

Primary Characterstics

Molecular Structure of Chloroquine

Chloroquine is also known as Chloroquina . Chloroquine Phosphate, Chloroquine Phosphate are the derivatives of ChloroquineChloroquine is also known as Chloroquina . Chloroquine Phosphate, Chloroquine Phosphate are the derivatives of Chloroquine It is of Synthetic origin. It belongs to Antiplasmodial pharmacological group on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group.

Its pKa is 8.4,10.

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Chloroquine's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage
25 mg /kg25 (25)As recommended.IV InfIn several infusions over 30 to 32 hours in severe and complicated malaria when patient is unable to take oral medication
300 mg300 (300)As recommended.POMaintenance After 6 hrs of initial dose, then OD for 2 days
500 mg500 (500)As recommended.PODose for Chloroquine phosphate: This dose is recommended in malaria and it should be given at the same day of each week.

Paedriatic Dosage (20kg)
3 mg/kg3 (3)As recommended.oralfor lupus erythematosis light sensitive skin eruption.
5 mg/kg5 (5)24 hourlyOralMaintenance after 6 hours of initial, for 2 days
12 mg/kg12 (12)24 hourlyOralInitially for Once

Neonatal Dosage (3kg)
6 mg/kg6 (6)24 hourlyOralMaintenance after 6 hours of initial, for 2 days
12 mg/kg12 (12)As recommended.OralInitially for Once

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Chloroquine

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