Gemfibrozil

Overview

Categories

Primary Characterstics

Indications

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Pharmacokinetics

Oral absorption of Gemfibrozil is found to be 100% . Volume of distribution is found to be 0.14l/kg and plasma protien binding is 95%. Renal Excretion accounts for 70% and plasma half life is 1.5 hr.

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Contraindications

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Drug Interactions

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Side Effects

The severe or irreversible adverse effects of Gemfibrozil, which give rise to further complications include Myositic syndrome.

Gemfibrozil produces potentially life-threatening effects which include Arrhythmias, Hypokalemia, Hypokalemia. which are responsible for the discontinuation of Gemfibrozil therapy.

The symptomatic adverse reactions produced by Gemfibrozil are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Impotence, GI symptoms, Dermatitis, Gall stones.

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Dosage

Gemfibrozil's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage

0.9 to 1.2 g1 (1.05)As recommended.POIn two divided doses given 30 min before the morning and evening meals

Paedriatic Dosage (20kg)

Not Recommended in this Age Group

Neonatal Dosage (3kg)

Not recommended in this age group

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

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Brands / Trade Names of Gemfibrozil

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Manufacturers of Gemfibrozil in Pakistan

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