Indomethacin
Overview
Indomethacin is NSAID (non-steroidal antinfalmmatory drug). Indomethacin is usually regarded as the father figure in the family of non steroidal agents. It relieves pain, reduces inflammation and fever. it, introduced in 1963, is a methylated indole derivative. Indomethacin is slightly more toxic but in certain circumstances more effective than aspirin. Indomethacin is prepared by chemical synthesis. Indomethacin is administered orally.
Categories
- 2 Analgesics, antipyretics, NSAIDs, antigout, and antirheumatics
- 2.1 Non-opioid analgesics
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Indomethacin's dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 50 to 200 mg | 120 (125) | As recommended. | PO | in divided doses with food. |
Paedriatic Dosage (20kg)
|
| 1 mg/kg | 1 (1) | 8 hourly | Oral | Recommended for 5-12 Years of Children |
Neonatal Dosage (3kg)
|
| 0.2 to 0.6 mg/kg | 0.4 (0.4) | 12 hourly | Intravenous | Dose for closure of ductus arteriosus |
High Risk Groups
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Warning / Precautions
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Storage Conditions
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Interference in Pathology
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Brands / Trade Names of
Indomethacin
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