Levodopa

Overview

Categories

Primary Characterstics

Molecular Structure of Levodopa

Levodopa is also known as L-dopa, L-dopa.Levodopa is also known as L-dopa, L-dopa. It is of Natural origin and belongs to Phenyl Alanine. It belongs to Dopamine agonist pharmacological group on the basis of mechanism of action and also classified in Antiparkinson Agents pharmacological group.The Molecular Weight of Levodopa is 197.20.

Its pKa is 2.3, 8.7,9.7, 13.4.

Indications

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Pharmacokinetics

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Contraindications

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Drug Interactions

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Side Effects

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Dosage

Levodopa's dosage details are as follows:
Dose Single Dose Frequency Route Instructions

Adult Dosage
100 mg100 (100)8 hourlyPOInitial, With carbidopa 25 mg, increase gradually as required .
750 to 2000 mg1400 (1375)24 hourlyPOIn div.doses, with carbidopa 75-100 mg, maintenance as required.

Paedriatic Dosage (20kg)
Safety not established

Neonatal Dosage (3kg)
No data regarding the neonatal dosage details of Levodopa is available.

High Risk Groups

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Warning / Precautions

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Storage Conditions

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Interference in Pathology

  • Serum tests for bilirubin, catecholamines, creatinine, glucose and uric acid
  • Urine tests for aminoacids, creatinine, creatinine clearance, oestrogens, glucose & Uric Acid
  • Urine tests for Ketone, Vanillylmandelic acid, 5-OH Indoleacetic Acid

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Brands / Trade Names of Levodopa

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Manufacturers of Levodopa in Pakistan

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