Methylergonovine
Overview
Methylergonovine is a semisynthetic ergot alkaloid and a derivative of ergonovine and is used for the prevention and control of postpartum and post-abortion hemorrhage. In general, the effects of all the ergot alkaloids appear to results from their actions as partial agonists or antagonists at adrenergic, dopaminergic, and tryptaminergic receptors. The spectrum of effects depends on the agent, dosage, species, tissue, and experimental or physiological conditions. All of the alkaloids of ergot significantly increase the motor activity of the uterus.
Categories
- 22 Obstetrics and gynecological preparations
- 22.1 Labor inducers/inhibitors
Primary Characterstics
Indications
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Pharmacokinetics
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Contraindications
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Side Effects
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Dosage
Indoramin (HCl)'s dosage details are as follows:
| Dose
|
Single Dose
|
Frequency
|
Route
|
Instructions
|
Adult Dosage
|
| 0.28 mg | 0.28 (0.28) | As recommended. | IV/IM | May be repeated as required, at intervals of 2-4 hours. |
| 0.2 mg | 0.2 (0.2) | 6 hourly | PO | |
Paedriatic Dosage (20kg)
|
| No data regarding the Paedriatic dosage details of Indoramin (HCl) is available. |
Neonatal Dosage (3kg)
|
| No data regarding the neonatal dosage details of Indoramin (HCl) is available. |
High Risk Groups
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Warning / Precautions
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Storage Conditions
Tablets
Store in a well closed container, Below 30°C. Protect from Sunlight and Heat.
Ampules
Store Below 15°C. Freezing is recommended. Protect from Sunlight.
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Interference in Pathology
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Brands / Trade Names of
Indoramin (HCl)
No Brands Available.
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Manufacturers of
Methylergonovine
in Pakistan
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