Severity N/A
Alcuronium (Cl) Interaction of Alcuronium (Cl) with Enflurane
Amitriptyline (HCl) Interaction of Amitriptyline (HCl) with Enflurane
Doxapram Interaction of Doxapram with Enflurane
Nitrous Oxide Interaction of Nitrous Oxide with Enflurane
Naloxone (HCl) Interaction of Naloxone (HCl) with Enflurane
Morphine Interaction of Morphine with Enflurane
Lignocaine Interaction of Lignocaine with Enflurane
Ketamine (HCl) Interaction of Ketamine (HCl) with Enflurane
Alcohol Interaction of Alcohol with Enflurane
Diazepam Interaction of Diazepam with Enflurane
Amitriptyline (HCl) Interaction of Amitriptyline (HCl) with Enflurane
Etomidate Interaction of Etomidate with Enflurane
Isoproterenol Interaction of Isoproterenol with Enflurane
Nitrous Oxide Interaction of Nitrous Oxide with Enflurane
Sotalol (HCl) Interaction of Sotalol (HCl) with Enflurane
Mivacurium (Cl) Interaction of Mivacurium (Cl) with Enflurane
Diazoxide Interaction of Diazoxide with Enflurane
Details: Enhanced hypotensive effect when Diazoxide given with Enflurane.
Interaction of Methotrexate with Enflurane
Propofol Interaction of Propofol with Enflurane
Details: Enflurane can be expected to increase the anesthetic or sedative and cardiorespiratory effects of Propofol Injectable Emulsion.
Moderate
Atracurium (Besylate) Interaction of Atracurium (Besylate) with Enflurane
Details: Enflurane may increases the effect of atracurium.
Management: Atracurium dosage must be reduced.
Interaction of Diltiazem (HCl) with Enflurane
Details: Additive pharmacological actions are reported when enflurane giving with diltiazem.Effects include risk of cardiac depression,hypotension,cardiovascular collapse and ventricular impairment.
Management: Hemodynamic and electrocardiographic monitoring are required during operation and discontinuation of diltiazem prior to surgery is not advised in coronary heart disease patient due to rebound effect.
Interaction of Isoniazid with Enflurane
Details: Metabolite of isoniazid, hydrazine, facilitates the defluorination of enflurane results in increased level of inorganic fluoride in plasma leads to nephrotoxicity.
Management: Closely monitor the renal function prior to surgery.
Interaction of Pancuronium (Br) with Enflurane
Details: Enflurane potentiate the effects of pancuronium.
Management: Dose of pancuronium should be reduce if necessary.
Interaction of Vecuronium (Br) with Enflurane
Details: Enflurane potentiates the effect of vecuronium.
Management: Dose of vecuronium should be reduced. Only specially trained health care providers should administer enflurane.
Interaction of Doxacurium with Enflurane
Details: Enflurane may initiate non depolarizing muscle relaxant effect.
Management: Enflurane dosage must be adjusted and administered by specially trained anesthologist.